SYGPeP™ · Functional Discovery

Bring a functional criterion earlier into biomolecule prioritization.

SYGPeP™ brings together SYG BIOTECH Functional Discovery & Prioritization programs, built with collaborating teams around a biological question and defined success criteria.

Functional discovery

Connect candidate selection earlier to a measurable experimental effect.

SYGPeP™ programs are built around a target, a library or candidate series, controls and success criteria defined with the partner.

Candidates

VHHs, DARPins, peptides and additional formats depending on the program.

Functional criterion

Introduce a relevant experimental readout into the prioritization logic.

Confirmation

Use SYGPeD™ or another appropriate quantitative method to confirm selected candidates where relevant.

Workflow

Scope → Prioritize → Confirm

01

Scope

Define the target, candidates, functional criterion and controls.

02

Prioritize

Apply the agreed workflow to select the most relevant candidates.

03

Confirm

Re-test selected candidates with an appropriate quantitative readout.

Partner programs

Discovery built around the partner’s biological question.

SYG BIOTECH

  • Experimental architecture and biosensing expertise
  • Study design and decision criteria
  • Quantitative analysis and documentation

Partner

  • Biological question and candidates
  • References or comparative methods when available
  • Scientific interpretation and extension decision

Developing VHHs, DARPins or peptides?

We can scope a functional discovery pilot program with a clear perimeter and defined success criteria.

Discuss SYGPeP™